Agenesis of Corpus Callosum

Important
It is possible that the main title of the report Agenesis of Corpus Callosumis not the name you expected.

Synonyms

ACC
Corpus Callosum, Agenesis

Disorder Subdivisions

Autosomal Recessive Inheritance ACC (e.g. Andermann syndrome)
X-Linked Dominant Inheritance ACC (e.g. ARX)
Acquired Form of ACC
Aicardi Syndrome

General Discussion

Agenesis of corpus callosum (ACC) is a rare disorder that is present at birth (congenital). It is characterized by a partial or complete absence (agenesis) of an area of the brain that connects the two cerebral hemispheres. This part of the brain is normally composed of transverse fibers. The cause of agenesis of corpus callosum is usually not known, but it can be inherited as either an autosomal recessive trait or an X-linked dominant trait. It can also be caused by an infection or injury during the twelfth to the twenty-second week of pregnancy (intrauterine) leading to developmental disturbance of the fetal brain. Intrauterine exposure to alcohol (Fetal alcohol syndrome) can also result in ACC. In some cases mental retardation may result, but intelligence may be only mildly impaired and subtle psychosocial symptoms may be present.

ACC is frequently diagnosed during the first two years of life. An epileptic seizure can be the first symptom indicating that a child should be tested for a brain dysfunction. The disorder can also be without apparent symptoms in the mildest cases for many years.
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Resources

March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains
NY
10605
Tel: (914)428-7100
Fax: (914)997-4763
800: (888)663-4637
Askus@marchofdimes.com
http://www.marchofdimes.com

The Arc (a national organization on mental retardation)
1010 Wayne Ave
Suite 650
Silver Spring
MD
20910
Tel: (301)565-3842
Fax: (301)565-3843
800: (800)433-5255
TDD: (817)277-0553
info@thearc.org
http://www.thearc.org/

National Hydrocephalus Foundation
12413 Centralia
Lakewood
CA
90715-1623
USA
Tel: (562)924-6666
Fax: (562)924-6666
800: (888)857-3434
nhf@earthlink.net
http://www.nhfonline.org

Guardians of Hydrocephalus Research Foundation
2618 Avenue Z
Brooklyn
NY
11235
Tel: (718)743-4473
Fax: (718)743-1171
800: (800)458-8655
GHRF2618@aol.comHydrocephalus Association
870 Market Street
Suite 705
San Francisco
CA
94102
USA
Tel: (415)732-7040
Fax: (415)732-7044
800: (888)598-3789
pip@hydroassoc.org
http://www.hydroassoc.org

Agenesis of the Corpus Callosum (ACC) Network
5749 Merrill Hall
Room 18
University of Maine
Orono
ME
04469-5749
Tel: (207)581-3119
Fax: (207)581-3120
um-acc@maine.eduNational Institute of Neurological Disorders and Stroke (NINDS)
31 Center Drive
8A07
Bethesda
MD
20892-2540
Tel: (301)496-5751
Fax: (301)402-2186
800: (800)352-9424
braininfo@ninds.nih.gov
http://www.ninds.nih.gov/

Birth Defect Research for Children
930 Woodcock Rd
Suite 225
Orlando
FL
32803
USA
Tel: (407)895-0802
Fax: (407)895-0824
staff@birthdefects.org
http://www.birthdefects.org

MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
150 Custer Court
Green Bay
WI
54301-1243
USA
Tel: (920)336-5333
Fax: (920)339-0995
800: (877)336-5333
mums@netnet.net
http://www.netnet.net/mums/

National Organization of Disorders of the Corpus Callosum
PMB 363 18032-C Lemon Drive
Yorba Linda
CA
92886
Tel: (714)747-0063
Fax: (714)693-0808
info@nodcc.org
http://www.nodcc.org

For a Complete Report:

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated: 8/8/2007
Copyright 1987, 1990, 2000, 2005, 2007 National Organization for Rare Disorders, Inc.

WebMD Medical Reference from the National Organization of Rare Disorders

Last Updated: August 08, 2007

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