User Reviews for Methotrexate (Anti-Rheumatic) oral

Been diagnosed with RA haven't started this drug yet. Have a script. Side effects scares me. Been taking glucosamine with chrondriton for 5 weeks and a dose pack of prednisone. Been off of prednisone for a week. Feel some tightness in wrists and left ankle otherwise feel fine. I have a colonoscopy scheduled later this month (routine) never had one before. I'm going to wait until I have it. Have an apt next month for bio identical hormone replacement. May wait until I start them also. I also have hashimotoes autoimmune disease. Genetic. No one in my family has RA that I am aware of. I don't want the RA to progress so I will try this medication and hope the side effects are not as bad as I think they will be. Then I'll give it a different rating.Read More Read Less

Woke up with terrible pain in all joints, worst in ankles & feet. Referred to rheumy but original tests neg. Thought to have osteo. Had steroid shots in fingers & wrists so I could could continue working. Had good results, but pain eventually got worse all over and was re-tested & dx with RA. Went on prednisone & metho, felt great after a few wks. But then she weaned me off prednisone as she said I could not stay on it. I hoped metho would do the trick as I did not want to go on a biologic. Finally had so much pain I relented and went on Humira. I did ok on it for a year, but then she said it was failing as my joints were not going down like the should, especially some fingers. So switched to Cimzia. Been on it for 1 1/2 yrs now and so far good. I do 2 injections in legs once a month, which I like better than the Humira. Take 3 1mg folic acid/day, 10 mg/wk metho and get blood checked every 8 weeks. I exercise and am able to resume all my normal activities that I could not do before. So I am pleased. I do think about the long term side effects, but I have such improved quality to my life now, that I just figure life is too short to live in pain if you don't have to. I figured if I didn't at least try something I would never know and I can always stop if it doesn't work. I had a lot of anxiety at first, but I am over that now, which I realize now probably made my pain worse. I am hoping for the best and just trying to live a full life the best I can. Still work part time for now. Try to eat better, think positively & exercising really helps me feel better. Yoga is great, wish I had discovered it a lot earlier in life. I wish everyone with RA the best. Read More Read Less

After 7 months started noticing my elbow/arm nodules were getting bigger. Also felt a lump starting on lumbar spine/coccyx. Doctor kept saying just a cyst on coccyx do nothing. I kept saying getting bigger. I insisted on a MRI - this huge lump is now 6"x 3"and the surgeon says it is Rheumatoid Nodule. I read Methotrexate can be cause of nodules or certainly makes them bigger. Folic Acid too makes nodules bigger. Be real careful of any lumps visual places and internal. Have quit this dangerous stuffRead More Read Less

Sick exhausted most of the time. Stopped taking because it wasn't working. Would rather have pain than spend day in bed sleeping

FINE

I have moderate to severe RA pain. Have been taking this for about 6 weeks (8 pills, once a week - with folic acid and hydroxychloroquine & 4 lortabs a day) - the "nodules" on my fingers are completely gone. The daily worsening of symptoms has stopped. I'm sleeping thru the night, not needing the lortab at night. Only side effect I see is a little more sleepiness the day I take mtx. The rest of the week I have more energy. I am able to go for 1/2 mile walks, and occasionally work out on nordic-trak - that i haven't been able to do for a couple of years. Rashes i've had for years (unrelated to RA) are going away. Still waiting for more easing of pain. So far - so good.Read More Read Less

I have taken this drug for about a year and find it most effective. there have been very few and mild side effects. (minor mouth sores) I started with 2 pills per week and worked my way up to 4 before I got relief. I can now function almost normally with little or no pain.

Dr isn't sure I have RA, but terrible pain and swelling from osteoarthritis, so he is trying this. Causes my mouth, tongue and lips to be sore, headaches, neck stiffness, some hair loss. I also have trouble going to sleep even tho I am exhausted almost all of the time. My hands are as swollen nor painful as they were, but cortizone injections work just as well or better. Have had one blood test to check liver. Find out in 2 days when I see dr. Been on mtx and folic acid for 5 wks now. Not sure it is worth it. Rather have shots, but will stick with it for a while longer if liver functions are okay. Read More Read Less

Been taking Methotrexate for 3 months and have been deathly ill for three weeks of them. Nausea, vomiting, severe stomach pain, fatigue, hair loss, diarrhea, headache, fever, and just let me die and get it over-with! Will never take this again!!! Feels like slow death!

have not really noticed a big change in pain level or fatigue

I have dark poop since yesterday, what can that be?

The only concern I have is my hair is thinning. I have stopped the methotrexate for now.

the medicine is not relieving my syptoms and causing me to loss my hair.

I have Ankylosing Spondylitis and take Humira 40mg.injections my arthritis was diagnosed in 2004.My dr put me on methotrexate last month when my A.S. levels increased. Since I toke my first dose of four 2.5mg once a week. My symptoms have gotten so much worse. Every inch of my spine is imflamed. I have made an appt. to see my dr. but when your given a drug it should help you not hurt you!

This medication only seemed to work while taken with steroids, after I was taken off steroids the swelling, muscle weakness and and joint pain returned.

sick for 36 hrs after taking.