Gilbert Syndrome

Important
It is possible that the main title of the report Gilbert Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

Constitutional Liver Dysfunction
Gilbert's Disease
Gilbert-Lereboullet Syndrome
Hyperbilirubinemia I
Meulengracht's Disease
Unconjugated Benign Bilirubinemia
Familial Nonhemolytic Jaundice

Disorder Subdivisions

None

General Discussion

Gilbert syndrome is a mild genetic liver disorder in which the body cannot properly process bilirubin, a yellowish waste product that is formed when the liver breaks down old or worn out red blood cells (hemolysis). Individuals with Gilbert syndrome have elevated levels of bilirubin (hyperbilirubinemia), which occurs because they have a reduced level of a specific liver enzyme required for elimination of bilirubin. Most affected individuals have no symptoms (asymptomatic) or may only exhibit mild yellowing of the skin, mucous membranes, and whites of the eyes (jaundice). Jaundice may not be apparent until adolescence. Bilirubin levels may increase following stress, exertion, dehydration alcohol consumption, fasting, and/or infection. In some individuals, jaundice may only be apparent when triggered by one of these conditions. Gilbert syndrome is inherited as an autosomal recessive trait.

Resources

March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
Tel: (914)428-7100
Fax: (914)997-4763
Tel: (888)663-4637
Email: Askus@marchofdimes.com
Internet: http://www.marchofdimes.com

Children's Liver Alliance
IN
Email: mail@liverkids.org.au
Internet: http://www.liverkids.org.au

NIH/National Digestive Diseases Information Clearinghouse
2 Information Way
Bethesda, MD 20892-3570
Tel: (301)654-3810
Fax: (301)907-8906
Tel: (800)891-5389
Email: nddic@info.niddk.nih.gov
Internet: http://www.niddk.nih.gov

Children's Liver Disease Foundation
36 Great Charles Street Queensway
Birmingham, Intl B3 3JY
United Kingdom
Tel: 0121-212-3839
Fax: 0121-212-4300
Email: info@childliverdisease.org
Internet: http://www.childliverdisease.org

Canadian Liver Foundation
2235 Sheppard Avenue
Suite 1500
Toronto, Ontario, Intl M2J 5B5
Canada
Tel: (416) 491-3353
Fax: (416) 491-4952
Tel: (800) 563-5483
Email: clf@liver.ca
Internet: http://www.liver.ca

British Liver Trust
Portman House
44 High Street
Ringwood, Intl BH24 1AG
United Kingdom
Tel: 01425 463080
Fax: 01425 470706
Email: info@britishlivertrust.org.uk
Internet: http://www.britishlivertrust.org.uk

MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
USA
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333
Email: mums@netnet.net
Internet: http://www.netnet.net/mums/

For a Complete Report:

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated: 10/2/2008
Copyright 1990, 1995, 1999, 2001, 2008 National Organization for Rare Disorders, Inc.

WebMD Medical Reference from the National Organization of Rare Disorders

Last Updated: October 02, 2008

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