Langerhans Cell Histiocytosis

Important
It is possible that the main title of the report Langerhans Cell Histiocytosis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

Histiocytosis-X
Eosinophilic Granuloma
Hand-Schuller Christian Syndrome
Letterer-Siwe Disease

Disorder Subdivisions

None

General Discussion

Langerhans cell histiocytosis (LCH) is a non-malignant proliferation of Langerhans cells (LC). Children and adults may have LCH in skin (macular, papular, ulcerative, or seborrheic rashes), bones (lytic lesions), lymph nodes, brain (pituitary, cerebrum and cerebellum) lung, liver, spleen, and bone marrow. Systemic symptoms may include fever, weight loss, draining ears, diabetes insipidus or other endocrinopathies.

Resources

Histiocytosis Association of America
332 North Broadway
Pitman, NJ 08071
Tel: (856)589-6606
Fax: (856)589-6614
Tel: (800)548-2758
Email: association@histio.org
Internet: http://www.histio.org

March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
Tel: (914)428-7100
Fax: (914)997-4763
Tel: (888)663-4637
Email: Askus@marchofdimes.com
Internet: http://www.marchofdimes.com

Diabetes Insipidus Foundation, Inc.
5203 New Prospect Court
Ellicott City, MD 21043
United States
Tel: (410)480-0880
Email: info@diabetesinsipidus.org
Internet: http://www.diabetesinsipidus.org

American Lung Association
61 Broadway, 6th Floor
New York, NY 10006
USA
Tel: (212)315-8700
Fax: (212)315-8870
Tel: (800)586-4872
Internet: http://www.lungusa.org

NIH/National Heart, Lung and Blood Institute Information Center
P.O. Box 30105
Bethesda, MD 20824-0105
Tel: (301)592-8573
Fax: (301)251-1223
Email: nhlbiinfo@rover.nhlbi.nih.gov

MUMS (Mothers United for Moral Support, Inc) National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
USA
Tel: (920)336-5333
Fax: (920)339-0995
Tel: (877)336-5333
Email: mums@netnet.net
Internet: http://www.netnet.net/mums/

Histiocytosis Association of Canada
29095 Okanagan Mission RPO
Kelowan, BC, V1W 1K2
Canada
Tel: 250-764-6104
Fax: 250-764-6104
Email: histio.canada@shaw.ca
Internet: http://www.histio.org/ca

For a Complete Report:

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated: 3/4/2009
Copyright 1987, 1989, 1992, 2002, 2003, 2004, 2007, 2009 National Organization for Rare Disorders, Inc.

WebMD Medical Reference from the National Organization of Rare Disorders

Last Updated: March 04, 2009

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